Noxopharm Shares Surge as Lupus Drug Clears Key Safety Tests

2 min read | February 04, 2025 11:03 AM AEDT | By Team Kalkine Media

Highlights

  • Noxopharm shares jumped 11% to 10cps following positive test results.
  • SOF-SKN, a topical lupus treatment, passed first-stage in vitro safety tests.
  • Final preclinical study to be completed before human trials begin in 2025.

Biotech firm Noxopharm (ASX:NOX) saw its shares surge 11% to 10cps on Tuesday morning after announcing that its experimental lupus medication, SOF-SKN, had successfully cleared initial safety testing.

The company confirmed that its topical Sofra drug candidate passed in vitro safety tests, moving it a step closer to human trials scheduled for 2025.

Breakthrough for Autoimmune Treatment

Lupus is a chronic autoimmune disease that causes the body’s immune system to attack its own tissues, leading to organ and tissue damage. SOF-SKN, a topical gel, is designed to target TLR7 receptors, which are believed to play a role in triggering the condition.

According to Noxopharm’s latest test results, the drug has shown no genetic mutation risks or cardiac toxicity, a crucial milestone in early-stage drug development. Additionally, an ultraviolet (UV) light exposure test confirmed the gel’s stability, ensuring safe use even after exposure to sunlight.

A final preclinical study remains before SOF-SKN progresses to human trials.

Market Reaction and Future Outlook

Despite the initial 11% surge, Noxopharm shares later settled at 8.5cps. The stock’s movement reflects investor optimism about the drug’s commercial potential while awaiting further developments.


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