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LONDON, GREATER LONDON, UNITED KINGDOM, June 16, 2025 /EINPresswire.com/ -- The Business Research Company’s Latest Report Explores Market Driver, Trends, Regional Insights - Market Sizing & Forecasts Through 2034
The gene silencing market size has experienced substantial growth in recent years. From $5.97 billion in 2024, it is slated to grow to $6.75 billion in 2025, showing a compound annual growth rate CAGR of 13.0%. Contributing significantly to this historic period growth is the burgeoning research in genetic therapies, groundbreaking advancements in RNA interference, the escalating prevalence of genetic disorders, surged investment in biotechnology, and an expansion in biopharmaceutical manufacturing capabilities.
What Is The Projected Future Growth Of The Gene Silencing Market Size?
Moreover, forecasting even faster growth in the upcoming years, the gene silencing market size is set to reach $10.95 billion by 2029 at a CAGR of 12.9%. Factors like broadening applications in rare diseases, revolutionary developments in delivery systems, heightened demand for personalized medicine, encouraging government initiatives, and flourishing partnerships between pharma and biotech companies are fuelling this forecast period growth. Key trends during this forecast period include targeted gene therapies, increasing adoption of CRISPR-based silencing approaches, sharpened focus on rare and orphan diseases, the advent of nanoparticle delivery technologies, and expansion into agricultural gene silencing applications.
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What Are The Key Drivers Propelling The Growth Of The Gene Silencing Market?
A key driver propelling the growth of the gene silencing market is the escalating prevalence of genetic disorders. Health conditions caused by DNA abnormalities, genetic disorders are being increasingly identified owing to advances in diagnostic technologies, raised awareness, and wider access to genetic testing. The rise in genetic disorders is attributed to increased parental age which raises the risk of genetic mutations being passed to offspring. Gene silencing, with its ability to selectively shut down the expression of erroneous or disease-causing genes, offers a hopeful solution to treating genetic disorders. For instance, in August 2023, Down Syndrome UK, a UK-based charity, reported an estimated 40,000 people in the UK affected by Down syndrome, with approximately 1 in every 800 babies born with the condition. Consequently, the increasing prevalence of genetic disorders is a major factor propelling the gene silencing market.
What Key Player Strategies Are Driving The Gene Silencing Market?
Major players operating in the gene silencing market include Roche Holding AG, Merck & Co. Inc., AstraZeneca plc, Novartis International AG, Thermo Fisher Scientific Inc., Danaher Corporation, Agilent Technologies Inc., Illumina Inc., Bio-Rad Laboratories Inc., Bio-Techne Corporation, Alnylam Pharmaceuticals Inc., GenScript Biotech Corporation, Oxford BioMedica plc, Ionis Pharmaceuticals Inc., Arrowhead Pharmaceuticals Inc., Dicerna Pharmaceuticals Inc., New England Biolabs Inc., Quark Pharmaceuticals Inc., Sirion Biotech GmbH, Benitec Biopharma Limited, GeneCopoeia Inc.,and Revvity Inc.
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What Are The Emerging Trends In The Gene Silencing Market?
One emerging trend in the gene silencing market is the emphasis major companies are giving to developing innovative technologies, such as small interfering RNA siRNA, to enhance precision and efficacy in gene therapy. Promoting the degradation of specific messenger RNA mRNA, small interfering RNA siRNA plays a pivotal role in the RNA interference RNAi pathway, preventing the production of disease-causing proteins. For example, in October 2024, Judo Bio Inc., a US-based biotechnology company, launched siRNA, a next-generation drug using small interfering RNA siRNA to silence genes. Unique features such as proprietary delivery systems including lipid nanoparticles or conjugated ligands ensuring efficient uptake by specific cells or tissues, and AI-driven platforms accelerating the identification of viable gene targets are included in the drug.
How Is The Gene Silencing Market Segmented?
The gene silencing market report covers the market segmentation as follows:
1 By Type: Transcriptional, Post-Transcriptional, Meiotic
2 By Gene Silencing: RNA Interference RNAi, Antisense Oligonucleotides ASOs, Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR Or Cas9 -Based Gene Silencing, Other Gene Silencings
3 By Application: Neurology, Oncology, Infectious Diseases, Metabolic Diseases, Therapeutics Manufacturing, Other Applications
4 By End-Users: Pharmaceutical And Biotechnology Companies, Research Institutes and Academic Centers, Hospitals, Clinics, Other End-Users
Subsegments:
1 By Transcriptional: DNA Methylation, Histone Modification
2 By Post-Transcriptional: RNA Interference RNAi, Antisense Oligonucleotides, MicroRNA miRNA Mediated Silencing
3 By Meiotic: Meiotic Gene Conversion, Transposable Element Silencing
What Are The Regional Insights In The Gene Silencing Market?
In 2024, North America was the largest region in the gene silencing market. However, Asia-Pacific is expected to be the fastest-growing region in the forecast period. The gene silencing market report contains regions comprising of Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, and Africa.
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