Novartis AG releases topline results from its pivotal global Phase III LUSTER-11 and LUSTER-22 studies
- The study was aimed at exploring the effectiveness and safety of the investigational oral, once-daily, DP2 receptor contender fevipiprant.
- The studies included patients who had improperly managed moderate-to-severe asthma, also known as GINA Steps 4 and 5, despite getting inhaled mid-to-high dose corticosteroids and at least one additional controller.
The combined analyses of the LUSTER trials were unable to meet the clinically important level for reducing the rate of moderate-to-severe exacerbation compared to placebo over a 52-week treatment period for either of the two doses of 150mg or 450 mg.
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