Anatara Life Sciences (ASX: ANR) swiftly progresses its clinical trials

3 min read | April 01, 2022 07:25 PM AEDT | By Aditi Sarkar

Highlights

  • Anatara Lifesciences is advancing well in its clinical trials in psychological functioning and irritable bowel syndrome, diarrhoea subtype (IBS-D)
  • The business prospect for non-prescription gastrointestinal disorders and IBS is US$8 billion in the US
  • ANR is looking forward to commercialising both human and animal gut health portfolios.

Anatara Lifesciences (ASX:ANR), a developer of evidence-based solutions for gastrointestinal diseases, is progressing its clinical trials in psychological functioning and irritable bowel syndrome, diarrhoea subtype (IBS-D). The company has expertise in developing products for human and animal health and is focused on building a pipeline of human gastrointestinal health products. 

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Recruitment is ongoing for two human trials with ethical approval

 

Trial sites 

Anticipated results 

GaRP in Irritable Bowel Syndrome – diarrhoea subtype (IBS-D) 

Paratus Clinical Research, CSIRO Nutrition and Health Research Clinic 

Interim – August 2022 

Final – January 2023 

3FDC in psychological functioning (anxiety, depression, stress) 

CSIRO Nutrition and Health Research Clinic 

Final – Late 2022 

There is a high instance of digestive disorders on a worldwide basis. This requires relief from both symptoms and the disease process, including irritable bowel syndrome (IBS). The gut-“brain axis” and the impact of the microbiome are also gaining traction. The GaRP complementary medicine offers a significant market opportunity to address these concerns while improving people's quality of life. 

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 irritable bowel syndrome

Image source: © Nupittu | Megapixl.com

Gastrointestinal ReProgramming (GaRP)

GaRP is Anatara's proof-based complementary medicine. It contains novel formulations of Bromelain (enzyme extracted from pineapple stems) and other synergistic GRAS (Generally Recognised as Safe) constituents. The combination and coating of these GaRP components have a favourable effect on the physiology of the gastrointestinal (GI) lining. It has a favourable impact on the microbiome (homeostasis & metabolites) and it enables absorption of valuable components in affected areas of the GI tract. 

" 3FDC" is the company's working reference to specific components from the overall GaRP product. Components of 3FDC are generally coated for targeted release ahead of the small intestine to permit delivery and influence in the large intestine. It is expected to have direct and indirect impacts, including helping in the homeostasis of a healthy microbiome.  

The delivery of these components and the impact on the microbiome are thought to be good for the gut-brain balance. Therefore, 3FDC components are selected to discover their impact on depression, anxiety and stress symptom in normal healthy individuals.

The company is looking forward to continuing these human clinical trials while progressing in commercialising both human and animal gut health portfolios.

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