This biotech stock is down 25% on Wednesday: find out why

December 21, 2023 03:44 AM AEDT | By Invezz
 This biotech stock is down 25% on Wednesday: find out why
Image source: Invezz

Argenx SE (NASDAQ:ARGX) says a late-stage trial of its candidate drug for an autoimmune condition failed to meet the primary or secondary endpoints. Its shares are down 25% at writing.

Here’s what we know so far

The said study tested its efgartigimod (subcutaneous) as a treatment of pemphigus – a disease that causes chronic blistering of the skin.

Argenx has decided in favour of not developing the drug for that autoimmune condition following today’s results. Still, Luc Truyen – its Chief Medical Officer said in a press release today:

2023 was a remarkable year of growth for Argenx across the business and we are poised to build on our success in 2024.

Last month, the Netherlands-based company reported $329 million in global net product sales for its third quarter. Argenx stock is now down close to 40% versus its year-to-date high.

Analyst reacts to today’s news

Note that the U.S. Food and Drug Administration (FDA) has already approved formulations of efgartigimod for myasthenia gravis.

But the biotech firm is now reviewing and may alter the design of a trial that’s testing the same drug in patients of bullous pemphigoid. Thomas Smith – a Leerink Partners analyst said in a research note this morning:

This study marks the second consecutive clinical setback, following the recent failure in primary immune thrombocytopenia in November.

Still, Smith maintained Argenx stock at “outperform” on Wednesday. Heading into today, he expected the company’s Vyvgart Hytrulo to eventually hit $716 million in global sales as pemphigus treatment and $1.6 billion as bullous pemphigoid treatment.

The post This biotech stock is down 25% on Wednesday: find out why appeared first on Invezz


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