FTSE 100 Edges Lower as Global Sentiment Shifts and AstraZeneca Stays Flat

July 04, 2025 12:00 AM BST | By Team Kalkine Media
 FTSE 100 Edges Lower as Global Sentiment Shifts and AstraZeneca Stays Flat
Image source: Shutterstock

Highlights

  • FTSE 100 displayed early softness with broader European indices trending lower
  • AstraZeneca’s Imfinzi secured European Union approval in a key cancer treatment category
  • Vodafone, Sainsbury’s, and BT led select gains despite broad index pressure

The FTSE 100 began the session lower, moving in a narrow band amid limited drivers and a subdued trading environment. Activity across markets remained tempered, with the United States observing Independence Day, removing cues from one of the world’s largest markets. Sentiment leaned cautious as tariff-related deadlines neared, shaping intraday sentiment.

Movements within the FTSE 100 were largely influenced by broad policy themes and sector positioning. With global benchmarks such as the DAX and CAC 40 also recording downward movement, the softness extended beyond national borders. The index reflected its alignment with broader regional caution rather than company-specific momentum.

Defensive Stocks Display Relative Strength

Despite the broader decline, select defensive segments stood out. Companies in telecommunications, grocery retail, and tobacco registered modest gains, indicating resilience amid macro headlines. Vodafone Group PLC (LSE:VOD), J Sainsbury PLC (LSE:SBRY), and British American Tobacco PLC (LSE:BATS) contributed positively to index composition in early trade.

The FTSE 100, known for its weightage in diversified and globally aligned sectors, occasionally sees divergence when defensive names move against general softness. The limited impact of broader developments on such sectors allowed them to resist overall downtrend pressure during the session.

AstraZeneca Receives Regulatory Approval for Imfinzi

AstraZeneca, a FTSE 100 constituent, remained steady after receiving European Union approval for its cancer treatment Imfinzi. The clearance allows use of the medication in specific bladder conditions around surgical timelines. Imfinzi had already been accepted in other regions, with the latest development highlighting progress within the company's healthcare innovation.

Despite the announcement, shares in AstraZeneca did not reflect significant intraday gains, with performance largely steady through morning sessions. Broader index movement appeared to overshadow the otherwise notable regulatory outcome. However, the update added a point of interest in an otherwise flat pharmaceutical segment.

European Sentiment Cools on Legislative Developments and Global Factors

Across the region, the mood stayed subdued. German and French benchmarks also traded lower, reflecting coordinated soft sentiment. Recent legislation approvals and tariff-related communication shaped broad movement across equities. With the tariff pause period approaching its end, markets moved with visible caution.

The FTSE 100 maintained close ties to global positioning, with defensive stocks gaining modest attention. Broader weakness from mining and resource segments offset isolated strength, resulting in a session where headline drivers were largely macroeconomic.


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