Highlights:
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Oncolytics Biotech reports a median progression-free survival benefit of 5.7 months in the BRACELET-1 trial for HR+/HER2- breast cancer.
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A Phase 2 study aimed at FDA accelerated approval is set to commence in the first half of 2025, focusing on 180 patients with advanced or metastatic breast cancer.
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Strategic collaborations with GCAR and PanCAN will enhance research efforts in pancreatic cancer, with initial efficacy results from the GOBLET study anticipated in the second half of 2025.
Oncolytics Biotech {NASDAQ:ONCY} has announced noteworthy advancements in the treatment of breast and pancreatic cancers, marking significant progress in its clinical research initiatives. The results from the BRACELET-1 trial in HR+/HER2- breast cancer indicate a median progression-free survival (PFS) benefit of 5.7 months for the cohort receiving the combination of pelareorep and paclitaxel, compared to those treated with standard chemotherapy alone. These promising findings pave the way for a forthcoming Phase 2 study, which aims to secure FDA accelerated approval. This study is scheduled to begin in the first half of 2025 and will involve 180 patients diagnosed with advanced or metastatic breast cancer.
In addition to its focus on breast cancer, Oncolytics Biotech is actively advancing studies related to gastrointestinal cancers. The company has identified several key milestones projected for 2025, highlighting its commitment to expanding its research portfolio in this critical area. Collaborations with the Global Coalition for Adaptive Research (GCAR) and the Pancreatic Cancer Action Network (PanCAN) are set to bolster research efforts specifically targeting pancreatic cancer, a disease notorious for its challenging prognosis.
The GOBLET study, which focuses on pancreatic cancer, aims to provide initial efficacy results that are anticipated in the second half of 2025. These collaborative research efforts underscore Oncolytics Biotech's dedication to exploring novel therapeutic options for patients facing this aggressive form of cancer.
Through these initiatives, Oncolytics Biotech demonstrates a robust commitment to advancing treatment modalities that could significantly enhance patient outcomes in both breast and pancreatic cancers. The company’s focus on innovative therapies, supported by promising trial results and strategic partnerships, reinforces its position as a key player in the evolving landscape of cancer treatment.