Biologic drugs or biologics are produced from living organisms or comprise components of any living organisms. These are genetically engineered proteins targeting specific parts of the immune system to treat the medical indication. The first biological drug was human insulin and was marketed in 1982.
Biologics are manufactured in a living system, for example, microorganism, or animal or plant cells. Many of the biologics are large and complex molecules. Most biologics are manufactured via recombinant DNA technology.