Allergan, Sightsavers and the IAPB Announce the 'Keep Sight' Initiative to Address Glaucoma in Ganjam, Odisha

• A unique initiative which joins an innovative eyecare biopharma leader with international charities to train healthcare professionals to diagnose and treat patients with glaucoma

• Glaucoma is the second most common cause of blindness worldwide1 and with adequate screening and diagnosis, vision loss can be prevented

Allergan, Sightsavers and the International Agency for the Prevention of Blindness (IAPB) today announced the launch of its unique joint initiative - 'Keep Sight India' - a community based glaucoma screening progamme to prevent glaucoma-related vision loss in Ganjam District, Odisha. The pilot kicked off in October 2019 in partnership with Sightsavers local partner, Sankara Eye Hospital.

The progamme provides training for healthcare professionals to screen at-risk populations, ensure early and accurate diagnosis and provide appropriate treatment and long-term care in an effort to make a positive impact on people with glaucoma at all levels of comprehensive eye care.

The first outreach camp was organised on December 3rd, 2019 on World Disability Day and subsequently four outreach camps were conducted under the pilot project. The outreach camps included services like vision testing, refraction, IOP measurement, fundus photography, spectacle dispensing, cataract identification, referral services and counselling services. To date 8276 people have been screened for glaucoma in these four outreach camps, from which 749 glaucoma suspects were identified and referred to the base hospital.²

Sightsavers India CEO, RN Mohanty said, "We are excited to be partnering with Allergan, an organisation with a long legacy in eyecare. Sightsavers too like Allergan is committed in finding and providing effective solutions for patients suffering with glaucoma, which is one of the leading causes of irreversible blindness. The typical barriers we face on ground include inadequate human resources, a lack of awareness and limited access to medical treatments. The partnership between Sightsavers and Allergan is an example of the vital associations that are needed to fight avoidable blindness and deliver better services at the community level."

Dr. SY Quraishi, Honorary Chairman Sightsavers India Board and former Chief Election Commissioner, India said, "Nearly 75% of sight loss can be cured or prevented, so it's an area where initiatives like this can have a strong impact where it is needed the most. I'm happy to know that people in and around Ganjam will become aware about Glaucoma and take adequate corrective measures which are now accessible via eye screening camps in the community and services at the Sankara Eye Hospital, Samarjhola."

"India will play a crucial role in meeting WHO's targets for eye health," said Joanna Conlon, Director of Development and Communications, IAPB. "The country is already at the forefront of delivering people - centered solutions for eye care. Keep Sight will work with Indian partners to support and extend India's successes around eye health and glaucoma. IAPB is committed to universal eye health. Sightsavers has decades of experience in delivering eye health in the region. Together with Allergan, they are keen to make a real difference for people with Glaucoma. Together, we will work to support India's eye care strategies."

"Allergan is honoured to partner with Sightsavers and IAPB on 'Keep Sight'; their wealth of knowledge and expertise, combined with our passion for science and solutions will have a real impact on our shared goal of reducing the high burden of irreversible blindness in the country. For almost two decades Allergan has been committed to developing novel approaches to preserve visual function and prevent blindness caused by glaucoma. 'Keep Sight' is an initiative that will make a real difference to people with glaucoma in India," said Gopinath Kesavan, Associate Director, Eyecare, Allergan India

Keep Sight India Project Update

The outputs of the programme achieved up until January 2020 are detailed below. The outputs include numbers from both outreach and hospital interventions.²

Plan for next Quarter (Jan-Mar 2020)

The next quarter of the project will focus primarily on the following activities:

• Training of Ophthalmologists on glaucoma care/management through International Council of Ophthalmology

• Strengthening interventions for follow-up compliance of patients diagnosed with glaucoma or treated under the programme

• Strengthening outreach interventions in terms of reducing per patient time in camps

• Continuous learning, training and skilling of the project team

• Development and dissemination of project communication materials in local language

About Glaucoma

Glaucoma is the second leading cause of blindness and a leading cause of irreversible blindness in India with at least 12 million people affected¹ and nearly 1.2 million people blind from the disease.1 More than 90 percent of cases of glaucoma remain undiagnosed in the community.¹ Glaucoma prevalence increases with age.¹ Several studies conducted in India reveal that the estimated prevalence of glaucoma varies from 1.7% to 3.5% in people above 40 years of age, and the differences are largely because of the regional and methodological variations.³ It is estimated at 11.2 million people for the age group 40 plus which is quite high.⁴

About Sightsavers

Sightsavers is an international organisation that works in more than 30 developing countries to prevent blindness, restore sight and advocate for social inclusion and equal rights for people with disabilities. It is a registered UK charity (Registered charity numbers 207544 and SC038110) www.sightsavers.org

Worldwide, 36 million people are blind, but 75 per cent of this sight loss can be treated or prevented.⁵ In the six decades since its foundation, Sightsavers has:

• Supported over 1.1 billion treatments for neglected tropical diseases⁶

• Carried out over 10.2 million operations to restore sight⁶

• Trained more than 795,427 primary eye care workers⁶

• Carried out rehabilitation training for 225,954 blind or low vision beneficiaries⁶

• Supported 62,908 blind or low vision children to gain a school education⁶

About the International Association for the Prevention of Blindness

The International Agency for the Prevention of Blindness (IAPB) is the coordinating membership organisation leading international efforts in blindness prevention activities. IAPB's mission is to eliminate the main causes of avoidable blindness and visual impairment by bringing together governments and non- governmental agencies to facilitate the planning, development and implementation of sustainable national eye care programmes.

For more information, please visit: www.iapb.org.

About Allergan plc

Allergan plc (NYSE: AGN), headquartered in Dublin, Ireland, is a global pharmaceutical leader focused on developing, manufacturing and commercializing branded pharmaceutical, device, biologic, surgical and regenerative medicine products for patients around the world. Allergan markets a portfolio of leading brands and best-in-class products primarily focused on four key therapeutic areas including medical aesthetics, eye care, central nervous system and gastroenterology. As part of its approach to delivering innovation for better patient care, Allergan has built one of the broadest pharmaceutical and device research and development pipelines in the industry.

1 www.nhp.gov.in/world-glaucoma-week_pg

2 Taken from output statistics in Keep Sight monthly reports. Further details available from Sightsavers' Media team

3 Saxena R, Singh D, Vashist P. Glaucoma: An emerging peril. Indian J Community Med [serial online] 2013 [cited 2020 Feb 19];38:135-7. Available from: www.ijcm.org.in/text.asp2013/38/3/135/116348

4 George R, Ve RS, Vijaya L. Glaucoma in India: estimated burden of disease. J Glaucoma. 2010 Aug;19(6):391-7. doi: 10.1097/IJG.0b013e3181c4ac5b.

5 www.sightsavers.org/protecting-sight/ Accessed February 2020

6 Taken from output statistics in Sightsavers' annual reports, aggregated since the founding of the charity. Further details available from Sightsavers' Media team